Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | WNT3A | P56704 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22892416 | 0.90 | NPC1 (0.60) | NPC1RAB9APOLBALDH1A1HPGD | |
| SCHEMBL25910342 | 0.83 | POLB (0.80) | NPC1RAB9APOLBALDH1A1LMNA | |
| SCHEMBL25910326 | 0.77 | MAPK1 (0.64) | NPC1RAB9APOLBALDH1A1HPGD | |
| SCHEMBL14133157 | 0.76 | POLB (0.73) | NPC1RAB9APOLBALDH1A1HPGD | |
| SCHEMBL25910323 | 0.74 | CNR2 (0.61) | RAB9AALDH1A1HPGDLMNAMAPT | |
| Hydrochloric Acid SCHEMBL28546374 | 0.74 | RAB9A (0.66) | NPC1RAB9APOLBALDH1A1HPGD | |
| SCHEMBL12057092 | 0.74 | POLB (0.79) | NPC1RAB9APOLBALDH1A1LMNA | |
| SCHEMBL2859054 | 0.73 | POLB (0.71) | NPC1RAB9APOLBALDH1A1HPGD | |
| SCHEMBL25910314 | 0.73 | KLKB1 (0.55) | NPC1RAB9AHPGDHDAC1 | |
| Hydrochloric Acid SCHEMBL6312908 | 0.72 | RAB9A (0.57) | NPC1RAB9APOLBHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234927-A1 | PROCESSES FOR PREPARING PLASMA KALLIKREIN INHIBITORS | REZOLUTE INC (US) | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234927-A1 | PROCESSES FOR PREPARING PLASMA KALLIKREIN INHIBITORS | C1R, C1S, KLKB1 | NPC1 1985/4885RAB9A 2525/4885POLB 1344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.