Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 11/20 | 0.66 |
| ▸ | NFATC1 | O95644 | 6/20 | 0.66 |
| ▸ | GSK3B | P49841 | 4/20 | 0.66 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.54 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.54 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.54 |
| ▸ | CDK2 | P24941 | 3/20 | 0.51 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.51 |
| ▸ | IGF1R | P08069 | 1/20 | 0.51 |
| ▸ | TDO2 | P48775 | 4/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25421202 | 0.80 | DYRK1A (1.00) | DYRK1ANFATC1GSK3BPDPK1TGFBR1 | |
| SCHEMBL30461701 | 0.80 | DYRK1A (1.00) | DYRK1ANFATC1GSK3BPDPK1TGFBR1 | |
| SCHEMBL26725844 | 0.80 | DYRK1A (0.59) | DYRK1ANFATC1GSK3BPDPK1TGFBR1 | |
| SCHEMBL17179566 | 0.79 | DYRK1A (1.00) | DYRK1ANFATC1GSK3BPDPK1TGFBR1 | |
| SCHEMBL26696137 | 0.77 | DYRK1A (0.80) | DYRK1ANFATC1GSK3BPDPK1TGFBR1 | |
| SCHEMBL16596104 | 0.74 | DYRK1A (0.70) | DYRK1ANFATC1GSK3BPDPK1TGFBR1 | |
| SCHEMBL26716515 | 0.74 | DYRK1A (0.59) | DYRK1ANFATC1GSK3BPDPK1TGFBR1 | |
| SCHEMBL31472564 | 0.73 | DYRK1A (1.00) | DYRK1ANFATC1GSK3BPDPK1TGFBR1 | |
| SCHEMBL18418490 | 0.73 | TDO2 (0.72) | DYRK1ANFATC1GSK3BPDPK1TGFBR1 | |
| SCHEMBL245511 | 0.72 | DYRK1A (0.61) | DYRK1ANFATC1GSK3BPDPK1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219459-A1 | 1H-PYRROLO[2,3-C]PYRIDINE COMPOUNDS AND APPLICATION THEREOF | Jumbo Drug Bank Co., Ltd. (CN) | 2023-08-02 | — | — | EP | disclosed |