Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 11/20 | 0.70 |
| ▸ | NFATC1 | O95644 | 6/20 | 0.70 |
| ▸ | GSK3B | P49841 | 4/20 | 0.70 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.53 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.53 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 2/20 | 0.50 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | IGF1R | P08069 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.49 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.49 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25421202 | 0.82 | DYRK1A (1.00) | DYRK1ANFATC1GSK3BPDPK1TGFBR1 | |
| SCHEMBL30461701 | 0.82 | DYRK1A (1.00) | DYRK1ANFATC1GSK3BPDPK1TGFBR1 | |
| SCHEMBL16697582 | 0.79 | IMPDH2 (0.59) | GSK3BMAPTMAPK1IMPDH2HSD17B10 | |
| SCHEMBL29563848 | 0.79 | IMPDH2 (0.59) | GSK3BMAPTMAPK1IMPDH2HSD17B10 | |
| SCHEMBL26696137 | 0.79 | DYRK1A (0.80) | DYRK1ANFATC1GSK3BPDPK1TGFBR1 | |
| SCHEMBL17179566 | 0.78 | DYRK1A (1.00) | DYRK1ANFATC1GSK3BPDPK1TGFBR1 | |
| SCHEMBL30557126 | 0.77 | BRD4 (0.55) | DYRK1ANFATC1GSK3BCDK2DYRK1B | |
| SCHEMBL10270837 | 0.76 | MAP3K7 (0.49) | DYRK1ANFATC1GSK3BAURKB | |
| SCHEMBL16708697 | 0.74 | TDO2 (0.49) | DYRK1ANFATC1HTR2AIMPDH2PIM1 | |
| SCHEMBL16697436 | 0.74 | TDO2 (0.61) | TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260007634-A1 | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF ALLERGIC DISEASES | KINKI UNIVERSITY (JP) | 2026-01-08 | — | — | US | disclosed |
| EP-4566599-A1 | PHARMACEUTICAL COMPOSITION FOR AMELIORATING ALLERGIC DISEASES | Kinki University (JP) | 2025-06-11 | — | — | EP | disclosed |
| US-20240124430-A1 | PHARMACEUTICAL COMPOSITION FOR AMELIORATING MALIGNANT DISEASES | KINKI UNIVERSITY (JP) | 2024-04-18 | — | — | US | disclosed |
| WO-2024029528-A1 | PHARMACEUTICAL COMPOSITION FOR AMELIORATING ALLERGIC DISEASES | 学校法人近畿大学 | 2024-02-08 | — | — | WO | disclosed |
| WO-2023234312-A1 | PHARMACEUTICAL COMPOSITION FOR AMELIORATING AUTOIMMUNE-TYPE DISEASES | 学校法人近畿大学 | 2023-12-07 | — | — | WO | disclosed |
| EP-4253372-A1 | PHARMACEUTICAL COMPOSITION FOR AMELIORATING MALIGNANT DISEASES | Kinki University (JP) | 2023-10-04 | — | — | EP | disclosed |
| WO-2020162638-A1 | COMPOSITION FOR AMELIORATING MALIGNANT TUMOR DISEASES | 学校法人近畿大学 | 2020-08-13 | — | — | WO | disclosed |
| US-9981963-B2 | 3-(1H-pyrazol-4-yl)-1H-pyrrolo[2,3-c]pyridine derivatives as NIK inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-29 | — | — | US | disclosed |
| EP-3049412-B1 | NEW 3-(1H-PYRAZOL-4-YL)-1H-PYRROLO[2,3-C]PYRIDINE DERIVATIVES AS NIK INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2017-07-12 | — | — | EP | disclosed |
| US-20160229851-A1 | NEW 3-(1H-PYRAZOL-4-YL)-1H-PYRROLO[2,3-c]PYRIDINE DERIVATIVES AS NIK INHIBITORS | ARGENTA DISCOVERY 2009 LIMITED (GB) | 2016-08-11 | — | — | US | disclosed |
| EP-3049412-A1 | NEW 3-(1H-PYRAZOL-4-YL)-1H-PYRROLO[2,3-c]PYRIDINE DERIVATIVES AS NIK INHIBITORS | Janssen Pharmaceutica, N.V. (BE) | 2016-08-03 | — | — | EP | disclosed |
| CN-105579452-A | New 3-(1H-pyrazol-4-yl)-1H-pyrrolo[2,3-c]pyridine derivatives as NIK inhibitors | JANSSEN PHARMACEUTICA NV | 2016-05-11 | — | — | CN | disclosed |
| WO-2015044269-A1 | NEW 3-(1H-PYRAZOL-4-YL)-1H-PYRROLO[2,3-c]PYRIDINE DERIVATIVES AS NIK INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2015-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260007634-A1 | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF ALLERGIC DISEASES | NFATC1, IL5, TRAF6 | DYRK1A 2182/4885NFATC1 1/4885GSK3B 164/4885 |
| US-20160229851-A1 | NEW 3-(1H-PYRAZOL-4-YL)-1H-PYRROLO[2,3-c]PYRIDINE DERIVATIVES AS NIK INHIBITORS | MAP3K14, MAP3K15, MAP3K13 | DYRK1A 718/4885NFATC1 177/4885GSK3B 573/4885 |
| US-20240124430-A1 | PHARMACEUTICAL COMPOSITION FOR AMELIORATING MALIGNANT DISEASES | MINK1, IKBKG, MAP3K20 | DYRK1A 2005/4885NFATC1 526/4885GSK3B 724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.