Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7365577 | 0.79 | HDAC1 (0.48) | KMT2AALOX15MEN1CYP1A2CHRM1 | |
| SCHEMBL2002867 | 0.79 | — | — | |
| SCHEMBL6393563 | 0.76 | KMT2A (0.44) | KMT2AALOX15BLMPMP22CYP3A4 | |
| SCHEMBL7859977 | 0.74 | ALDH1A1 (0.53) | KMT2AALOX15BLMPMP22CYP3A4 | |
| SCHEMBL18822226 | 0.74 | ALDH1A1 (0.53) | KMT2AALOX15BLMPMP22CYP3A4 | |
| SCHEMBL11371695 | 0.74 | TSHR (0.48) | KMT2AMEN1TSHRCA1CA2 | |
| SCHEMBL1001541 | 0.74 | — | — | |
| SCHEMBL3688083 | 0.73 | CA2 (0.39) | KMT2AALOX15BLMPMP22CYP3A4 | |
| SCHEMBL21182210 | 0.73 | CA1 (0.48) | KMT2AALOX15BLMPMP22CYP3A4 | |
| SCHEMBL5506710 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |