Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 4/20 | 0.79 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.79 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.54 |
| ▸ | BRAF | P15056 | 15/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | RAF1 | P04049 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16049194 | 0.89 | CSF1R (1.00) | CSF1RPDGFRAPDGFRBBRAFKDR | |
| SCHEMBL25910807 | 0.88 | CSF1R (0.61) | CSF1RPDGFRABRAFRAF1 | |
| SCHEMBL25910409 | 0.85 | CSF1R (0.56) | CSF1RPDGFRAPDGFRBBRAFKDR | |
| SCHEMBL25910298 | 0.85 | CSF1R (0.75) | CSF1RPDGFRAPDGFRBBRAFKDR | |
| SCHEMBL25910690 | 0.84 | CSF1R (0.64) | CSF1RPDGFRAPDGFRBBRAFKDR | |
| SCHEMBL25909911 | 0.83 | CSF1R (0.55) | CSF1RPDGFRAPDGFRBBRAFRAF1 | |
| SCHEMBL25911300 | 0.79 | CSF1R (0.76) | CSF1RPDGFRAPDGFRBKDR | |
| SCHEMBL3061583 | 0.73 | BRAF (0.61) | BRAFKDRRAF1 | |
| SCHEMBL13884087 | 0.72 | BRAF (0.60) | BRAFKDRRAF1 | |
| SCHEMBL3051121 | 0.72 | BRAF (0.60) | BRAFKDRRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |