Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 17/20 | 0.56 |
| ▸ | PDGFRA | P16234 | 10/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.53 |
| ▸ | KDR | P35968 | 2/20 | 0.51 |
| ▸ | FLT3 | P36888 | 6/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25910298 | 0.85 | CSF1R (0.75) | CSF1RPDGFRAPDGFRBKDRFLT3 | |
| SCHEMBL25910565 | 0.85 | CSF1R (0.79) | CSF1RPDGFRAPDGFRBKDRBRAF | |
| SCHEMBL25910291 | 0.84 | CSF1R (0.52) | CSF1RPDGFRAPDGFRBKDRFLT3 | |
| SCHEMBL25910690 | 0.84 | CSF1R (0.64) | CSF1RPDGFRAPDGFRBKDRFLT3 | |
| SCHEMBL25911300 | 0.83 | CSF1R (0.76) | CSF1RPDGFRAPDGFRBKDRFLT3 | |
| SCHEMBL25910028 | 0.81 | CSF1R (0.53) | CSF1RPDGFRAPDGFRBKDRFLT3 | |
| SCHEMBL25910279 | 0.74 | CSF1R (0.43) | CSF1RPDGFRAPDGFRBKDRFLT3 | |
| SCHEMBL25910179 | 0.73 | CSF1R (0.37) | CSF1RPDGFRAPDGFRBKDRFLT3 | |
| SCHEMBL16049194 | 0.72 | CSF1R (1.00) | CSF1RPDGFRAPDGFRBKDRFLT3 | |
| SCHEMBL25910429 | 0.72 | KDM4E (0.38) | PDE3BPDE3AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |