Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 11/20 | 0.64 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.64 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.64 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | RIOK2 | Q9BVS4 | 2/20 | 0.39 |
| ▸ | FLT3 | P36888 | 4/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.37 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | TEK | Q02763 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25910298 | 0.92 | CSF1R (0.75) | CSF1RPDGFRAPDGFRBKDRRIOK2 | |
| SCHEMBL25910697 | 0.88 | CSF1R (0.51) | CSF1RPDGFRAPDGFRBKDRRIOK2 | |
| SCHEMBL25910409 | 0.84 | CSF1R (0.56) | CSF1RPDGFRAPDGFRBKDRFLT3 | |
| SCHEMBL25910565 | 0.84 | CSF1R (0.79) | CSF1RPDGFRAPDGFRBKDRBRAF | |
| SCHEMBL25910551 | 0.83 | CSF1R (0.49) | CSF1RPDGFRAPDGFRBKDRRIOK2 | |
| SCHEMBL25913590 | 0.82 | CSF1R (0.43) | CSF1RPDGFRAPDGFRBRIOK2AAK1 | |
| SCHEMBL25910292 | 0.79 | CSF1R (0.57) | CSF1RPDGFRAPDGFRBKDRFLT3 | |
| SCHEMBL25911300 | 0.79 | CSF1R (0.76) | CSF1RPDGFRAPDGFRBKDRFLT3 | |
| SCHEMBL16046823 | 0.78 | CSF1R (1.00) | CSF1RPDGFRAPDGFRBKDRFLT3 | |
| SCHEMBL25910691 | 0.77 | CSF1R (0.38) | CSF1RPDGFRAPDGFRBKDRRIOK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |