Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 3/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 12/20 | 0.32 |
| ▸ | KDR | P35968 | 5/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 2/20 | 0.31 |
| ▸ | AXL | P30530 | 3/20 | 0.30 |
| ▸ | MST1R | Q04912 | 1/20 | 0.30 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25914939 | 0.91 | CSF1R (0.36) | CSF1RPDGFRBPDGFRACYP2C9LCK | |
| SCHEMBL25910916 | 0.90 | CSF1R (0.35) | CSF1RPDGFRBPDGFRACYP2C9LCK | |
| SCHEMBL25910813 | 0.86 | CSF1R (0.41) | CSF1RPDGFRBPDGFRACYP2C9LCK | |
| SCHEMBL25914916 | 0.85 | CSF1R (0.36) | CSF1RPDGFRBPDGFRACYP2C9LCK | |
| SCHEMBL25910033 | 0.84 | CSF1R (0.51) | CSF1RPDGFRBPDGFRACYP2C9LCK | |
| SCHEMBL25913615 | 0.84 | MET (0.32) | CSF1RPDGFRBPDGFRACYP2C9LCK | |
| SCHEMBL25910692 | 0.84 | CSF1R (0.40) | CSF1RPDGFRBPDGFRACYP2C9LCK | |
| SCHEMBL25914740 | 0.81 | CSF1R (0.35) | CSF1RPDGFRBPDGFRACYP2C9LCK | |
| SCHEMBL25914570 | 0.77 | CSF1R (0.42) | CSF1RPDGFRBPDGFRACYP2C9LCK | |
| SCHEMBL25910799 | 0.77 | BRAF (0.46) | CSF1RPDGFRBPDGFRALCKKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |