Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 4/20 | 0.32 |
| ▸ | AXL | P30530 | 3/20 | 0.32 |
| ▸ | LCK | P06239 | 2/20 | 0.31 |
| ▸ | KIT | P10721 | 2/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.31 |
| ▸ | FLT3 | P36888 | 2/20 | 0.31 |
| ▸ | PLK4 | O00444 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | PRKACA | P17612 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | ABL2 | P42684 | 1/20 | 0.31 |
| ▸ | FRK | P42685 | 1/20 | 0.31 |
| ▸ | MST1R | Q04912 | 1/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.31 |
| ▸ | MERTK | Q12866 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25914114 | 0.88 | SCN9A (0.34) | P2RX3 | |
| SCHEMBL25910918 | 0.84 | CSF1R (0.35) | METAXLLCKKITPDGFRA | |
| SCHEMBL25913574 | 0.81 | GABRA1 (0.34) | — | |
| SCHEMBL25910692 | 0.79 | CSF1R (0.40) | METAXLLCKKITPDGFRA | |
| SCHEMBL25910813 | 0.78 | CSF1R (0.41) | METAXLLCKKITPDGFRA | |
| SCHEMBL25915039 | 0.77 | — | — | |
| SCHEMBL25910033 | 0.76 | CSF1R (0.51) | METAXLLCKKITPDGFRA | |
| SCHEMBL25914939 | 0.76 | CSF1R (0.36) | METLCKKITPDGFRAFLT3 | |
| SCHEMBL25914988 | 0.75 | P2RX3 (0.31) | LCKKITPDGFRAFLT3P2RX3 | |
| SCHEMBL25910916 | 0.74 | CSF1R (0.35) | METLCKKITPDGFRAFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |