Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.59 |
| ▸ | HNF4A | P41235 | 2/20 | 0.59 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.56 |
| ▸ | BAD | Q92934 | 1/20 | 0.56 |
| ▸ | DHFR | P00374 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | ERN1 | O75460 | 4/20 | 0.53 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.53 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.49 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.49 |
| ▸ | ACLY | P53396 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21157447 | 0.86 | MCL1 (0.57) | ACMSDHNF4ABCL2L1BADMCL1 | |
| SCHEMBL9973581 | 0.85 | ACMSD (0.59) | ACMSDHNF4ADHFRMCL1ERN1 | |
| SCHEMBL92217 | 0.82 | NR4A2 (0.51) | ACMSDHNF4ABCL2L1BADDHFR | |
| SCHEMBL2255019 | 0.81 | BCL2L1 (0.72) | ACMSDHNF4ABCL2L1BADDHFR | |
| SCHEMBL2255015 | 0.81 | BCL2L1 (0.72) | ACMSDHNF4ABCL2L1BADDHFR | |
| SCHEMBL25741026 | 0.80 | ERN1 (0.54) | ERN1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL1709589 | 0.79 | TYMS (0.44) | ACMSDHNF4ABCL2L1BADDHFR | |
| SCHEMBL28926892 | 0.79 | ERN1 (0.53) | ACMSDHNF4ADHFRMCL1ERN1 | |
| SCHEMBL12991957 | 0.78 | ERN1 (0.53) | ERN1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL68982 | 0.78 | ACMSD (0.70) | ACMSDHNF4ADHFRMCL1DCLRE1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111978740-B | Solid-phase renewable silicone rubber and preparation method and application thereof | 广东工业大学 | 2022-05-20 | — | — | CN | claimed |
| CN-113403635-B | Method for preparing N-substituted pyrrolidone derivative | 五邑大学 | 2022-05-03 | — | — | CN | claimed |
| CN-111978740-A | Solid-phase renewable silicone rubber and preparation method and application thereof | 广东工业大学 | 2020-11-24 | — | — | CN | claimed |
| CN-111978740-B | Solid-phase renewable silicone rubber and preparation method and application thereof | 广东工业大学 | 2022-05-20 | — | — | CN | disclosed |
| CN-113403635-B | Method for preparing N-substituted pyrrolidone derivative | 五邑大学 | 2022-05-03 | — | — | CN | disclosed |
| CN-113403635-A | Method for preparing N-substituted pyrrolidone derivative | 五邑大学 | 2021-09-17 | — | — | CN | disclosed |
| CN-111978740-A | Solid-phase renewable silicone rubber and preparation method and application thereof | 广东工业大学 | 2020-11-24 | — | — | CN | disclosed |
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |
| US-4330291-A | Nitrated coupler compounds useful in direct dyeing and simultaneous oxidation and direct dyeing of keratinic fibers | SOCIETE ANONYME DITE: L'OREAL (FR) | 1982-05-18 | — | — | US | disclosed |