Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 16/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 8/20 | 0.48 |
| ▸ | FLT3 | P36888 | 4/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | KIT | P10721 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 7/20 | 0.43 |
| ▸ | MET | P08581 | 2/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25909902 | 1.00 | CSF1R (0.48) | CSF1RPDGFRBPDGFRAFLT3LCK | |
| SCHEMBL25911492 | 0.88 | TLR7 (0.34) | CSF1RPDGFRBPDGFRAFLT3LCK | |
| SCHEMBL25910282 | 0.88 | TLR7 (0.34) | CSF1RPDGFRBPDGFRAFLT3LCK | |
| SCHEMBL25910558 | 0.84 | CSF1R (0.55) | CSF1RPDGFRBPDGFRAFLT3LCK | |
| SCHEMBL25910174 | 0.84 | ADORA2A (0.44) | CSF1RPDGFRBPDGFRA | |
| SCHEMBL25910699 | 0.82 | CSF1R (0.51) | CSF1RPDGFRBPDGFRAFLT3LCK | |
| SCHEMBL25912717 | 0.81 | P2RX3 (0.36) | KDRFGFR1 | |
| SCHEMBL25911490 | 0.80 | KCNH2 (0.37) | — | |
| SCHEMBL25912711 | 0.79 | RAF1 (0.35) | CSF1RPDGFRBPDGFRAFLT3LCK | |
| SCHEMBL25909794 | 0.78 | CSF1R (0.75) | CSF1RPDGFRBPDGFRAFLT3LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |