Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 4/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | KIT | P10721 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.48 |
| ▸ | WEE1 | P30291 | 2/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 3/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 2/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25319475 | 0.83 | CSF1R (0.47) | CSF1RPDGFRBPDGFRALCKKIT | |
| SCHEMBL25317059 | 0.83 | PDGFRB (0.47) | CSF1RPDGFRBPDGFRALCKKIT | |
| SCHEMBL25911644 | 0.82 | CSF1R (0.47) | CSF1RPDGFRBPDGFRALCKKIT | |
| SCHEMBL25911604 | 0.79 | CSF1R (0.53) | CSF1RPDGFRBPDGFRALCKKIT | |
| SCHEMBL25911369 | 0.77 | CSF1R (0.45) | CSF1RPDGFRBPDGFRALCKKIT | |
| SCHEMBL21872971 | 0.75 | CSF1R (0.53) | CSF1RPDGFRBPDGFRALCKKIT | |
| SCHEMBL25909907 | 0.75 | CSF1R (0.75) | CSF1RPDGFRBPDGFRALCKKIT | |
| SCHEMBL25911557 | 0.75 | PDGFRB (0.42) | CSF1RPDGFRBPDGFRALCKKIT | |
| SCHEMBL25912017 | 0.73 | CSF1R (0.49) | CSF1RPDGFRBPDGFRALCKKIT | |
| SCHEMBL25911715 | 0.73 | CSF1R (0.43) | CSF1RPDGFRBPDGFRALCKKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |