Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 4/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 5/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.31 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.31 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.31 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.31 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.31 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.31 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.31 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25914415 | 0.87 | PDGFRB (0.35) | CSF1RPDGFRBPDGFRALCKKIT | |
| SCHEMBL25912017 | 0.85 | CSF1R (0.49) | CSF1RPDGFRBPDGFRALCKKIT | |
| SCHEMBL25317492 | 0.84 | PDGFRB (0.35) | CSF1RPDGFRBPDGFRALCKKIT | |
| SCHEMBL25914850 | 0.84 | EGFR (0.35) | CSF1RPDGFRBPDGFRALCKKIT | |
| SCHEMBL25317059 | 0.84 | PDGFRB (0.47) | CSF1RPDGFRBPDGFRALCKKIT | |
| SCHEMBL25911603 | 0.83 | CSF1R (0.48) | CSF1RPDGFRBPDGFRALCKKIT | |
| SCHEMBL25910178 | 0.80 | CSF1R (0.52) | CSF1RPDGFRBPDGFRALCKKIT | |
| SCHEMBL29222872 | 0.79 | CSF1R (0.54) | CSF1RPDGFRBPDGFRALCKKIT | |
| SCHEMBL30825676 | 0.79 | CSF1R (0.54) | CSF1RPDGFRBPDGFRALCKKIT | |
| SCHEMBL25319458 | 0.78 | CSF1R (0.52) | CSF1RPDGFRBPDGFRALCKKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |