Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.48 |
| ▸ | ARG2 | P78540 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 3/20 | 0.47 |
| ▸ | NOS1 | P29475 | 2/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 7/20 | 0.46 |
| ▸ | BHMT | Q93088 | 4/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2591185 | 1.00 | ARG1 (0.48) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL2591183 | 1.00 | ARG1 (0.48) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL8746612 | 0.85 | NOS2 (0.45) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL29393779 | 0.84 | ARG1 (0.61) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL36935 | 0.84 | ARG1 (0.61) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL29378137 | 0.84 | ARG1 (0.61) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL36933 | 0.84 | ARG1 (0.61) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL36934 | 0.84 | ARG1 (0.61) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL23085771 | 0.83 | SLC7A5 (0.54) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL2128359 | 0.83 | SLC7A5 (0.54) | ARG1ARG2NOS2NOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2563809-A2 | STABLE AQUEOUS MIA/CD-RAP FORMULATIONS | Scil Technology GmbH (DE) | 2013-03-06 | — | — | EP | disclosed |
| WO-2011134979-A9 | STABLE AQUEOUS MIA/CD-RAP FORMULATIONS | SCIL TECHNOLOGY GMBH (DE) | 2012-08-16 | — | — | WO | disclosed |
| WO-2011134979-A2 | STABLE MIA/CD-RAP FORMULATION | SCIL TECHNOLOGY GMBH (DE) | 2011-11-03 | — | — | WO | disclosed |