Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 2/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30825676 | 0.81 | CSF1R (0.54) | CSF1RPDGFRBLCKKITCYP2C9 | |
| SCHEMBL29222872 | 0.81 | CSF1R (0.54) | CSF1RPDGFRBLCKKITCYP2C9 | |
| SCHEMBL25912095 | 0.81 | LCK (0.42) | CSF1RPDGFRBLCKKITCYP2C9 | |
| SCHEMBL25317059 | 0.80 | PDGFRB (0.47) | CSF1RPDGFRBLCKKITCYP2C9 | |
| SCHEMBL25911644 | 0.78 | CSF1R (0.47) | CSF1RPDGFRBLCKKITCYP2C9 | |
| SCHEMBL25911715 | 0.78 | CSF1R (0.43) | CSF1RPDGFRBLCKKITCYP2C9 | |
| SCHEMBL25911369 | 0.77 | CSF1R (0.45) | CSF1RPDGFRBLCKKITCYP2C9 | |
| SCHEMBL21872971 | 0.76 | CSF1R (0.53) | CSF1RPDGFRBLCKKITCYP2C9 | |
| SCHEMBL25911557 | 0.75 | PDGFRB (0.42) | CSF1RPDGFRBLCKKITCYP2C9 | |
| SCHEMBL25319475 | 0.73 | CSF1R (0.47) | CSF1RPDGFRBLCKKITCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |