Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL345613 | 0.82 | KDM4E (0.36) | — | |
| SCHEMBL1160881 | 0.79 | MEN1 (0.33) | CNR2KDM5AKDM4C | |
| SCHEMBL27193312 | 0.79 | CNR2 (0.32) | CNR2 | |
| SCHEMBL13603259 | 0.70 | KDM4E (0.44) | KDM5AKDM4C | |
| SCHEMBL870085 | 0.69 | KDM4E (0.36) | — | |
| SCHEMBL1699332 | 0.69 | ATR (0.36) | CNR2KDM5A | |
| SCHEMBL1094625 | 0.69 | L3MBTL1 (0.42) | CNR2KDM4C | |
| SCHEMBL3398126 | 0.69 | NAPRT (0.39) | KDM4C | |
| SCHEMBL71090 | 0.69 | SMARCA2 (0.41) | CNR2KDM5A | |
| SCHEMBL2302256 | 0.68 | KDM4E (0.42) | KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011139891-A1 | PYRIDONE AMIDES AND ANALOGS EXHIBITING ANTI-CANCER AND ANTI-PROLIFERATIVE ACTIVITES | DECIPHERA PHARMACEUTICALS, LLC (US) | 2011-11-10 | — | — | WO | disclosed |