SCHEMBL2591237

SCHEMBL2591237

Brc1cccnc1C(c1ccccc1)c1ncccc1Br.Cc1cc(C)c(N2CCN(c3c(C)cc(C)cc3C)C2=[Ru](Cl)Cl)c(C)c1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29446250 0.77
SCHEMBL28429466 0.75
SCHEMBL30008059 0.75
SCHEMBL14574917 0.74
SCHEMBL29784948 0.74
SCHEMBL17267904 0.73 ALDH1A1 (0.33) MEN1ALDH1A1KMT2A
SCHEMBL1662433 0.72 ALDH1A1 (0.34) ALDH1A1
SCHEMBL14784045 0.72 SLC6A2 (0.48) ALDH1A1KMT2A
SCHEMBL3827602 0.71 SLC6A2 (0.47) ALDH1A1KMT2A
SCHEMBL29362942 0.71 SLC6A2 (0.47) ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11673130-B2 Catalyst system containing a metathesis catalyst and at least one phenolic compound and a process for metathesis of nitrile-butadiene rubber (NBR) using the catalyst system ARLANXEO DEUTSCHLAND GMBH (DE) 2023-06-13 US claimed
US-20220032279-A1 CATALYST SYSTEM CONTAINING A METATHESIS CATALYST AND AT LEAST ONE PHENOLIC COMPOUND AND A PROCESS FOR METATHESIS OF NITRILE-BUTADIENE RUBBER (NBR) USING THE CATALYST SYSTEM ARLANXEO DEUTSCHLAND GMBH (DE) 2022-02-03 US claimed
EP-3713989-B1 HIGH MOLECULAR WEIGHT POLYOXYETHYLENE WITH DEEP GLASS TEMPERATURE MADE USING THE GRAFTING THROUGH METHOD COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2021-06-30 EP claimed
US-10973847-B2 Core-to-surface polymerization for the synthesis of star polymers and uses thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2021-04-13 US claimed
US-20200377652-A1 HIGH MOLECULAR WEIGHT POLYOXYALKYLENE WITH LOW GLASS TRANSITION TEMPERATURE, PRODUCED BY THE GRAFTING THROUGH METHOD COVESTRO DEUTSCHLAND AG (DE) 2020-12-03 US claimed
EP-3087104-B1 METHOD FOR CONTROLLED METATHESIS DEPOLYMERIZATION OF NATURAL RUBBER FROM NATURAL RUBBER LATEX MICHELIN & CIE (FR) 2019-11-13 EP claimed
EP-3489278-A1 HIGH MOLECULAR WEIGHT POLYOXYETHYLENE WITH DEEP GLASS TEMPERATURE MADE USING THE GRAFTING THROUGH METHOD Covestro Deutschland AG (DE) 2019-05-29 EP claimed
EP-2897992-B1 FUNCTIONALIZED RESINS OBTAINED VIA OLEFIN METATHESIS EXXONMOBIL CHEMICAL PATENTS INC (US) 2017-11-08 EP claimed
US-9181360-B2 Polymers prepared by ring opening / cross metathesis EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-11-10 US claimed
US-8669330-B2 Olefin triblock polymers via ring-opening metathesis polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-03-11 US claimed
US-8623962-B2 Olefin functionalization by metathesis reaction EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-01-07 US claimed
US-20130281626-A1 Polyolefin Compositions and Methods of Production Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2013-10-24 US claimed
US-20130137829-A1 Functionalization of Vinyl Terminated Polymers by Ring Opening Cross Metathesis EXXONMOBIL CHEMICAL PATENTS INC. 2013-05-30 US claimed
US-20130041122-A1 Polymers Prepared By Ring Opening / Cross Metathesis EXXONMOBIL CHEMICAL PATENTS INC. 2013-02-14 US claimed
US-20130030126-A1 Olefin Functionalization By Metathesis Reaction EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-01-31 US claimed
US-8283419-B2 Olefin functionalization by metathesis reaction EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-10-09 US claimed
US-20120245294-A1 Olefin Triblock Polymers via Ring-Opening Metathesis Polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2012-09-27 US claimed
US-20120245290-A1 Diblock Copolymers Prepared by Cross Metathesis EXXONMOBIL CHEMICAL PATENTS INC. 2012-09-27 US claimed
US-20090318647-A1 Olefin Functionalization By Metathesis Reaction EXXONMOBIL CHEMICAL PATENTS INC. 2009-12-24 US claimed
US-20080227851-A1 LAULIMALIDE AND LAULIMALIDE ANALOGS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2008-09-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080227851-A1 LAULIMALIDE AND LAULIMALIDE ANALOGS SSB, LPXN, LTA MEN1 326/4885ALDH1A1 3502/4885KMT2A 4481/4885
US-10973847-B2 Core-to-surface polymerization for the synthesis of star polymers and uses thereof STARD7, MB, STARD3 MEN1 4099/4885ALDH1A1 4092/4885KMT2A 3797/4885
US-20130030126-A1 Olefin Functionalization By Metathesis Reaction MAX, AP1M1, AP3M1 MEN1 793/4885ALDH1A1 3705/4885KMT2A 3469/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.