Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 2/20 | 0.50 |
| ▸ | CSF1R | P07333 | 2/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.50 |
| ▸ | RIOK2 | Q9BVS4 | 3/20 | 0.41 |
| ▸ | BRAF | P15056 | 13/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25913590 | 0.93 | CSF1R (0.43) | PDGFRBCSF1RPDGFRARIOK2BRAF | |
| SCHEMBL25913006 | 0.90 | CSF1R (0.40) | PDGFRBCSF1RPDGFRARIOK2BRAF | |
| SCHEMBL16049203 | 0.85 | CSF1R (0.68) | PDGFRBCSF1RPDGFRARIOK2BRAF | |
| SCHEMBL25913001 | 0.84 | BRAF (0.35) | PDGFRBCSF1RPDGFRABRAFLCK | |
| SCHEMBL25910298 | 0.81 | CSF1R (0.75) | PDGFRBCSF1RPDGFRARIOK2BRAF | |
| SCHEMBL25909917 | 0.81 | PDGFRB (0.52) | PDGFRBCSF1RPDGFRABRAFMAPK14 | |
| SCHEMBL25911299 | 0.78 | CSF1R (0.52) | PDGFRBCSF1RPDGFRALCKKIT | |
| SCHEMBL25910421 | 0.78 | PDGFRB (0.48) | PDGFRBCSF1RPDGFRARIOK2BRAF | |
| SCHEMBL25910422 | 0.78 | PDGFRB (0.47) | PDGFRBCSF1RPDGFRABRAFMAPK14 | |
| SCHEMBL25910419 | 0.78 | PDGFRB (0.46) | PDGFRBCSF1RPDGFRABRAFMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |