Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 2/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | RIOK2 | Q9BVS4 | 4/20 | 0.41 |
| ▸ | BRAF | P15056 | 11/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.37 |
| ▸ | GSK3A | P49840 | 2/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.36 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25912909 | 0.93 | PDGFRB (0.50) | CSF1RPDGFRAPDGFRBRIOK2BRAF | |
| SCHEMBL25913006 | 0.93 | CSF1R (0.40) | CSF1RPDGFRAPDGFRBRIOK2BRAF | |
| SCHEMBL25913001 | 0.84 | BRAF (0.35) | CSF1RPDGFRAPDGFRBBRAF | |
| SCHEMBL30467033 | 0.84 | BRAF (0.35) | CSF1RPDGFRAPDGFRBBRAF | |
| SCHEMBL25910551 | 0.82 | CSF1R (0.49) | CSF1RPDGFRAPDGFRBRIOK2BRAF | |
| SCHEMBL25910690 | 0.82 | CSF1R (0.64) | CSF1RPDGFRAPDGFRBRIOK2BRAF | |
| SCHEMBL25912757 | 0.80 | P2RX3 (0.36) | RIOK2BRAF | |
| SCHEMBL16049203 | 0.79 | CSF1R (0.68) | CSF1RPDGFRAPDGFRBRIOK2BRAF | |
| SCHEMBL25911299 | 0.78 | CSF1R (0.52) | CSF1RPDGFRAPDGFRB | |
| SCHEMBL25910797 | 0.75 | PDGFRB (0.39) | CSF1RPDGFRAPDGFRBRIOK2BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |