Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 10/20 | 0.35 |
| ▸ | CSF1R | P07333 | 4/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 2/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30467033 | 1.00 | BRAF (0.35) | BRAFCSF1RPDGFRAHDAC8HDAC6 | |
| SCHEMBL25912751 | 0.85 | MAPK8 (0.39) | BRAFCSF1RPDGFRBMAPK8IRAK4 | |
| SCHEMBL25913590 | 0.84 | CSF1R (0.43) | BRAFCSF1RPDGFRAPDGFRB | |
| SCHEMBL25912909 | 0.84 | PDGFRB (0.50) | BRAFCSF1RPDGFRAPDGFRBLCK | |
| SCHEMBL25911299 | 0.83 | CSF1R (0.52) | CSF1RPDGFRAPDGFRBLCKKIT | |
| SCHEMBL25914331 | 0.82 | DYRK1A (0.35) | BRAFHDAC8HDAC6IRAK4 | |
| SCHEMBL25913006 | 0.81 | CSF1R (0.40) | BRAFCSF1RPDGFRAPDGFRBIRAK4 | |
| SCHEMBL25911790 | 0.79 | CSF1R (0.53) | BRAFCSF1RPDGFRAPDGFRBLCK | |
| SCHEMBL25912706 | 0.73 | CSF1R (0.43) | BRAFCSF1RPDGFRAPDGFRBLCK | |
| SCHEMBL16048014 | 0.72 | CSF1R (0.47) | CSF1RPDGFRAPDGFRBMAPK8LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |