Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.34 |
| ▸ | TACR3 | P29371 | 4/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25327145 | 1.00 | RORC (0.34) | RORCTACR3PSEN1PSEN2APH1B | |
| SCHEMBL25327071 | 0.99 | RORC (0.34) | RORCTACR3PSEN1PSEN2APH1B | |
| SCHEMBL25329140 | 0.91 | CYP3A4 (0.33) | ALDH1A1KDM1ALMNAPOLB | |
| SCHEMBL25327381 | 0.91 | CYP3A4 (0.33) | ALDH1A1KDM1ALMNAPOLB | |
| SCHEMBL25327222 | 0.90 | PSEN1 (0.37) | TACR3PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL25327423 | 0.90 | PSEN1 (0.37) | TACR3PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL25325404 | 0.89 | RIPK1 (0.36) | ALDH1A1KDM1APOLB | |
| SCHEMBL25327793 | 0.88 | PSEN1 (0.34) | TACR3PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL30523066 | 0.88 | PSEN1 (0.34) | TACR3PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL25326007 | 0.85 | PSEN1 (0.36) | RORCTACR3PSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146991-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |