Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | FPR1 | P21462 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11983426 | 0.81 | MAPK1 (0.43) | RAB9ASIRT2SIRT1SIRT3HSD17B10 | |
| SCHEMBL16153996 | 0.76 | RAB9A (1.00) | RAB9AHSD17B10KDM4EMAPTMEN1 | |
| SCHEMBL12877694 | 0.75 | MAPK1 (0.41) | RAB9ASIRT2SIRT1SIRT3HSD17B10 | |
| SCHEMBL703931 | 0.72 | MAPT (0.72) | RAB9AMAPTKMT2AALDH1A1POLB | |
| SCHEMBL28856012 | 0.72 | HSD17B10 (0.50) | RAB9AHSD17B10KDM4EKMT2AALDH1A1 | |
| SCHEMBL24987981 | 0.71 | SMN1; SMN2 (0.76) | RAB9AHSD17B10KDM4EMAPTMEN1 | |
| SCHEMBL24129892 | 0.70 | HSD17B10 (0.41) | RAB9AHSD17B10KDM4EKMT2AALDH1A1 | |
| SCHEMBL6191819 | 0.70 | KDM4E (0.40) | RAB9AHSD17B10KDM4EMAPTMEN1 | |
| SCHEMBL24129893 | 0.70 | HSD17B10 (0.56) | HSD17B10MAPTALDH1A1POLBLMNA | |
| SCHEMBL8345138 | 0.69 | SIRT2 (0.59) | RAB9ASIRT2SIRT1SIRT3HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718592-B2 | Oxadiazole derivative | Sumitomo Pharma Co., Ltd. (JP) | 2023-08-08 | — | — | US | disclosed |
| US-11718592-B2 | Oxadiazole derivative | Sumitomo Pharma Co., Ltd. (JP) | 2023-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718592-B2 | Oxadiazole derivative | OXA1L, SCN1A, CACNA1A | RAB9A 2204/4885SIRT2 291/4885SIRT1 166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.