Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.59 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.59 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.59 |
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | GCGR | P47871 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15442034 | 0.86 | HSD17B10 (0.59) | MAPTTRPM8TP53MDM2ALDH1A1 | |
| SCHEMBL28297288 | 0.85 | GAA (0.58) | TARBP2MAPTGABRA2GABRB2TP53 | |
| SCHEMBL8026733 | 0.83 | SIRT2 (0.56) | SIRT2SIRT1SIRT3ALPLTARBP2 | |
| SCHEMBL8342056 | 0.81 | MAPK1 (0.50) | SIRT2SIRT1SIRT3GCGRKDM4E | |
| SCHEMBL8036853 | 0.76 | SIRT2 (0.54) | SIRT2SIRT1SIRT3ALPLTARBP2 | |
| SCHEMBL4007745 | 0.76 | SIRT2 (0.48) | SIRT2SIRT1SIRT3ALPLTARBP2 | |
| SCHEMBL4604916 | 0.75 | ALPL (0.56) | SIRT2SIRT1SIRT3ALPLTARBP2 | |
| SCHEMBL28746458 | 0.75 | MAPT (0.42) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL26659457 | 0.74 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL20567843 | 0.74 | ALOX5 (0.63) | SIRT2SIRT1SIRT3MAPTTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5888941-A | Carbozamides with antifungal activity | J. URIACH & CIA. S.A. (ES) | 1999-03-30 | — | — | US | disclosed |
| EP-0783502-A1 | NEW CARBOXAMIDES WITH ANTIFUNGAL ACTIVITY | J. URIACH & CIA. S.A. (ES) | 1997-07-16 | — | — | EP | disclosed |
| WO-1997005131-A1 | NEW CARBOXAMIDES WITH ANTIFUNGAL ACTIVITY | J. URIACH & CIA. S.A. (ES) | 1997-02-13 | — | — | WO | disclosed |