Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25914399 | 0.84 | TSHR (0.63) | NPC1RAB9APOLBHPGDSMN1; SMN2 | |
| SCHEMBL25914400 | 0.84 | MAOB (0.53) | NPC1RAB9AL3MBTL1MAPTPOLB | |
| SCHEMBL28494999 | 0.78 | NOTUM (0.68) | NPC1RAB9AL3MBTL1MAPTPOLB | |
| SCHEMBL30889117 | 0.76 | NPC1 (0.63) | NPC1RAB9AL3MBTL1MAPTPOLB | |
| SCHEMBL30889116 | 0.76 | NPC1 (0.63) | NPC1RAB9AL3MBTL1MAPTPOLB | |
| SCHEMBL15912496 | 0.75 | MAPT (0.55) | NPC1RAB9AL3MBTL1MAPTPOLB | |
| SCHEMBL25914397 | 0.75 | HDAC6 (0.48) | NPC1RAB9AL3MBTL1MAPTPOLB | |
| SCHEMBL8589773 | 0.75 | NPC1 (0.61) | NPC1RAB9AL3MBTL1MAPTPOLB | |
| SCHEMBL5117429 | 0.75 | ALDH1A1 (0.68) | NPC1RAB9AL3MBTL1MAPTPOLB | |
| SCHEMBL9610048 | 0.73 | DGAT1 (0.72) | NPC1RAB9AL3MBTL1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230265061-A1 | OXADIAZOLE DERIVATIVE | Sumitomo Pharma Co., Ltd. (JP) | 2023-08-24 | — | — | US | disclosed |
| US-20230265061-A1 | OXADIAZOLE DERIVATIVE | Sumitomo Pharma Co., Ltd. (JP) | 2023-08-24 | — | — | US | disclosed |
| US-11718592-B2 | Oxadiazole derivative | Sumitomo Pharma Co., Ltd. (JP) | 2023-08-08 | — | — | US | disclosed |
| US-11718592-B2 | Oxadiazole derivative | Sumitomo Pharma Co., Ltd. (JP) | 2023-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718592-B2 | Oxadiazole derivative | OXA1L, SCN1A, CACNA1A | NPC1 1348/4885RAB9A 2204/4885L3MBTL1 2454/4885 |
| US-20230265061-A1 | OXADIAZOLE DERIVATIVE | OXA1L, SCN1A, CACNA1A | NPC1 1348/4885RAB9A 2204/4885L3MBTL1 2454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.