SCHEMBL25915401

SCHEMBL25915401

c1ccc(N(c2ccccc2)c2cccc(-c3cccc4c3Oc3ccc(-c5cccc(N(c6ccccc6)c6ccccc6)c5)c5cccc-4c35)c2)cc1

nearest known ligand 0.30

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CRHBP P24387 1/20 0.30
CRHR2 Q13324 1/20 0.30
KEAP1 Q14145 1/20 0.30
NFE2L2 Q16236 1/20 0.30
BRD4 O60885 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25915340 0.90 CRHBP (0.32) CRHBPCRHR2KEAP1NFE2L2
SCHEMBL25915398 0.88 CRHBP (0.31) CRHBPCRHR2KEAP1NFE2L2
SCHEMBL24126546 0.88 CRHBP (0.31) CRHBPCRHR2KEAP1NFE2L2
SCHEMBL27351197 0.88 KDM4E (0.43) BRD4
SCHEMBL27351200 0.85 KDM4E (0.40)
SCHEMBL27351332 0.85 KDM4E (0.40)
SCHEMBL27351190 0.85 KDM4E (0.40)
SCHEMBL27351188 0.85 KDM4E (0.40)
SCHEMBL27351202 0.85 KDM4E (0.40)
SCHEMBL26164305 0.84 KDM4E (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230240134-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LT MATERIALS CO., LTD. (KR) 2023-07-27 US disclosed
US-20230240134-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LT MATERIALS CO., LTD. (KR) 2023-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230240134-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME CRY1, CYP1A1, CYP1B1 CRHBP 4280/4885CRHR2 3341/4885KEAP1 401/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.