SCHEMBL25916557

SCHEMBL25916557

Cc1ccc(C(=O)Nc2ccc(N)cc2-c2nc3ccccc3s2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 14/20 0.57
RXFP1 Q9HBX9 5/20 0.57
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
NPSR1 Q6W5P4 2/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2C9 P11712 1/20 0.56
HPGD P15428 2/20 0.55
TP53 P04637 4/20 0.55
SMN1; SMN2 Q16637 4/20 0.55
KDM4E B2RXH2 2/20 0.55
NPC1 O15118 2/20 0.55
RAB9A P51151 2/20 0.55
ALDH1A1 P00352 2/20 0.54
HSD17B10 Q99714 3/20 0.54
TDP1 Q9NUW8 2/20 0.54
CYP1A2 P05177 1/20 0.54
ATIC P31939 1/20 0.54
APP P05067 1/20 0.54
POLB P06746 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25916502 0.91 MAPT (0.61) MAPTRXFP1MEN1KMT2ANPSR1
SCHEMBL25916549 0.91 HPGD (0.62) MAPTRXFP1MEN1KMT2ANPSR1
SCHEMBL25916475 0.89 MAPT (0.70) MAPTRXFP1MEN1KMT2ANPSR1
SCHEMBL25916534 0.87 MAPT (0.57) MAPTRXFP1MEN1KMT2ANPSR1
SCHEMBL25916306 0.87 HPGD (0.62) MAPTRXFP1MEN1KMT2ANPSR1
SCHEMBL30362642 0.87 HPGD (0.62) MAPTRXFP1MEN1KMT2ANPSR1
SCHEMBL25916518 0.85 MAPT (0.70) MAPTRXFP1MEN1KMT2ANPSR1
SCHEMBL30211749 0.83 MAPT (0.55) MAPTRXFP1MEN1KMT2ANPSR1
SCHEMBL25916307 0.83 MAPT (0.55) MAPTRXFP1MEN1KMT2ANPSR1
SCHEMBL16602328 0.81 KDM4E (0.73) MAPTRXFP1MEN1KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230235190-A1 FLUORESCENT COMPOSITION COMPRISING AT LEAST ONE BENZAZOLE COMPOUND FOR THE SECUREMENT OF PRODUCTS Crime Science Technology (FR) 2023-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230235190-A1 FLUORESCENT COMPOSITION COMPRISING AT LEAST ONE BENZAZOLE COMPOUND FOR THE SECUREMENT OF PRODUCTS TUBB3, TUBA3C, PHB1 MAPT 318/4885RXFP1 1340/4885MEN1 1798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.