Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | PRKCB | P05771 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25916140 | 0.78 | KHK (0.32) | SIGMAR1 | |
| SCHEMBL20214950 | 0.76 | SIGMAR1 (0.38) | SIGMAR1PRKCB | |
| SCHEMBL2927085 | 0.76 | SIGMAR1 (0.38) | SIGMAR1PRKCB | |
| SCHEMBL2927087 | 0.76 | SIGMAR1 (0.38) | SIGMAR1PRKCB | |
| SCHEMBL13993897 | 0.76 | SIGMAR1 (0.38) | SIGMAR1PRKCB | |
| SCHEMBL15292087 | 0.76 | SIGMAR1 (0.38) | SIGMAR1PRKCB | |
| SCHEMBL2225916 | 0.76 | SIGMAR1 (0.38) | SIGMAR1PRKCB | |
| SCHEMBL21831491 | 0.76 | SIGMAR1 (0.38) | SIGMAR1PRKCB | |
| SCHEMBL21831861 | 0.76 | SIGMAR1 (0.38) | SIGMAR1PRKCB | |
| SCHEMBL16250451 | 0.76 | SIGMAR1 (0.38) | SIGMAR1PRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146991-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |