Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KHK | P50053 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.30 |
| ▸ | HTR2B | P41595 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23058708 | 0.79 | KHK (0.31) | KHKSIGMAR1 | |
| SCHEMBL25325404 | 0.78 | RIPK1 (0.36) | — | |
| SCHEMBL25916905 | 0.78 | SIGMAR1 (0.34) | SIGMAR1 | |
| SCHEMBL25914192 | 0.77 | RORC (0.34) | DGAT1 | |
| SCHEMBL25327145 | 0.77 | RORC (0.34) | DGAT1 | |
| SCHEMBL25329140 | 0.77 | CYP3A4 (0.33) | — | |
| SCHEMBL25327381 | 0.77 | CYP3A4 (0.33) | — | |
| SCHEMBL19301999 | 0.76 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL25327222 | 0.76 | PSEN1 (0.37) | — | |
| SCHEMBL25325833 | 0.76 | PSEN1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146991-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |