Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 12/20 | 0.35 |
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18898059 | 1.00 | MCHR1 (0.35) | MCHR1NCF1KDM4EHTR2AHTR2C | |
| SCHEMBL8255348 | 0.83 | HTR2A (0.38) | MCHR1NCF1HTR2AHTR2CSLC6A2 | |
| SCHEMBL18959352 | 0.83 | HTR2A (0.38) | MCHR1NCF1HTR2AHTR2CSLC6A2 | |
| SCHEMBL14224494 | 0.83 | HTR2A (0.38) | MCHR1NCF1HTR2AHTR2CSLC6A2 | |
| SCHEMBL27654643 | 0.82 | KDM4E (0.33) | MCHR1KDM4E | |
| SCHEMBL19226483 | 0.80 | HTR2A (0.33) | MCHR1NCF1HTR2AHTR2C | |
| SCHEMBL19114994 | 0.80 | HTR2A (0.33) | MCHR1NCF1HTR2AHTR2C | |
| SCHEMBL21081438 | 0.79 | KDM4E (0.35) | MCHR1NCF1KDM4EHTR2AHTR2C | |
| SCHEMBL24477230 | 0.77 | ALDH1A1 (0.39) | MCHR1NCF1HTR2AHTR2CSLC6A2 | |
| SCHEMBL21739319 | 0.74 | L3MBTL3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219479-A1 | PYRIMIDINE CARBOXAMIDE COMPOUND AND APPLICATION THEREOF | Shanghai Meiyue Biotech Development Co., Ltd. (CN) | 2023-08-02 | — | — | EP | disclosed |