Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 8/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15185922 | 0.89 | MAOA (0.53) | RECQLGAAFAAHHDAC3HDAC1 | |
| SCHEMBL23587955 | 0.89 | RECQL (0.50) | RECQLGAATSHRSMN1; SMN2FAAH | |
| SCHEMBL7345186 | 0.89 | FAAH (0.61) | RECQLGAAFAAHMAPTALDH1A1 | |
| SCHEMBL15764778 | 0.88 | MAOA (0.47) | RECQLGAATSHRSMN1; SMN2FAAH | |
| SCHEMBL29060568 | 0.87 | FAAH (0.64) | GAAFAAHMEN1KMT2ASLC6A5 | |
| SCHEMBL15840422 | 0.87 | MAOA (0.47) | RECQLGAATSHRSMN1; SMN2FAAH | |
| SCHEMBL9664722 | 0.87 | FAAH (0.64) | GAAFAAHMEN1KMT2ASLC6A5 | |
| SCHEMBL9664810 | 0.87 | FAAH (0.64) | GAAFAAHMEN1KMT2ASLC6A5 | |
| SCHEMBL7520244 | 0.87 | FAAH (0.64) | GAAFAAHMEN1KMT2ASLC6A5 | |
| SCHEMBL9664822 | 0.87 | FAAH (0.64) | GAAFAAHMEN1KMT2ASLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220737-A2 | OLIGONUCLEOTIDES HAVING A SYNTHETIC BACKBONE AND SYNTHESIS THEREOF | ADARX PHARMACEUTICALS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| EP-4219718-A2 | COMPOSITIONS AND METHODS FOR MODULATING COMPLEMENT FACTOR B EXPRESSION | Ionis Pharmaceuticals, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |