SCHEMBL25917853

SCHEMBL25917853

CCC1(N)CC(C(C)(C)C)C1

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 2/20 0.31
GRIN3B O60391 2/20 0.31
GRIN1 Q05586 2/20 0.31
GRIN2A Q12879 2/20 0.31
GRIN2B Q13224 2/20 0.31
GRIN2C Q14957 2/20 0.31
GRIN3A Q8TCU5 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21058249 0.76 ALDH1A1 (0.40)
SCHEMBL25951401 0.72
SCHEMBL26456069 0.72 KDM4E (0.31)
SCHEMBL27618524 0.72 POLB (0.37)
SCHEMBL24791547 0.70 GRIN2D (0.34) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL25745655 0.67 KDM4E (0.30)
SCHEMBL23795835 0.67 GRIN2D (0.32) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL24230431 0.65 GRIN2D (0.43) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL24974577 0.65
SCHEMBL24508042 0.64 APLNR (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230218575-A1 MICROSUSPENSION OF AN MDM2 INHIBITOR AND THERAPEAUTIC APPLICATIONS THEREOF ASCENTAGE PHARMA GROUP CORP LIMITED (CN) 2023-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230218575-A1 MICROSUSPENSION OF AN MDM2 INHIBITOR AND THERAPEAUTIC APPLICATIONS THEREOF MDM2, TP53, TP53BP1 GRIN2D 2641/4885GRIN3B 3272/4885GRIN1 2009/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.