Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27267755 | 0.98 | LMNA (0.41) | LMNAL3MBTL1SMN1; SMN2NPSR1MMP1 | |
| SCHEMBL26292989 | 0.85 | — | — | |
| SCHEMBL7081089 | 0.85 | — | — | |
| SCHEMBL26292991 | 0.85 | — | — | |
| SCHEMBL19091099 | 0.84 | MME (0.46) | LMNAL3MBTL1SMN1; SMN2NPSR1MMP1 | |
| SCHEMBL23340135 | 0.82 | LMNA (0.44) | LMNAL3MBTL1SMN1; SMN2NPSR1MMP1 | |
| SCHEMBL27267931 | 0.82 | LMNA (0.41) | LMNAL3MBTL1SMN1; SMN2NPSR1MMP1 | |
| SCHEMBL24307188 | 0.81 | ALDH1A1 (0.33) | LMNAALDH1A1CYP2D6CYP2C19PSMB5 | |
| SCHEMBL19091245 | 0.81 | RECQL (0.50) | LMNAL3MBTL1SMN1; SMN2NPSR1MMP1 | |
| SCHEMBL24774067 | 0.79 | PSMB5 (0.33) | ALDH1A1PSMB5TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4218929-A1 | ANTI-EGFR ANTIBODIES AND ANTIBODY DRUG CONJUGATES | AbbVie Inc. (US) | 2023-08-02 | — | — | EP | disclosed |