SCHEMBL25918283

SCHEMBL25918283

CCc1ccc(Oc2ccc(NC(=O)c3ccccc3C(=O)O)cc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.66
KMT2A Q03164 3/20 0.66
L3MBTL1 Q9Y468 2/20 0.66
MAPK1 P28482 1/20 0.65
GFER P55789 1/20 0.65
ALDH1A1 P00352 3/20 0.60
RAB9A P51151 3/20 0.60
NPC1 O15118 2/20 0.60
SMN1; SMN2 Q16637 2/20 0.60
POLB P06746 2/20 0.60
GAA P10253 1/20 0.60
CRHBP P24387 1/20 0.60
FNTA P49354 1/20 0.60
FNTB P49356 1/20 0.60
CRHR2 Q13324 1/20 0.60
LMNA P02545 2/20 0.58
MITF O75030 1/20 0.58
PNLIP P16233 4/20 0.58
MAPT P10636 1/20 0.58
PTPN2 P17706 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7829395 0.92 ALDH1A1 (0.70) MEN1KMT2AGFERALDH1A1RAB9A
SCHEMBL13927137 0.89 MEN1 (0.81) MEN1KMT2AL3MBTL1MAPK1GFER
SCHEMBL13927136 0.89 MEN1 (0.81) MEN1KMT2AL3MBTL1MAPK1GFER
SCHEMBL25918279 0.87 ALDH1A1 (0.65) MEN1KMT2AGFERALDH1A1RAB9A
SCHEMBL12189610 0.87 MEN1 (0.78) MEN1KMT2AL3MBTL1MAPK1GFER
SCHEMBL12700426 0.85 GFER (0.78) MEN1KMT2AL3MBTL1MAPK1GFER
SCHEMBL675767 0.85 MEN1 (0.71) MEN1KMT2AL3MBTL1MAPK1GFER
SCHEMBL13927142 0.84 MEN1 (0.74) MEN1KMT2AL3MBTL1MAPK1GFER
SCHEMBL155094 0.83 PGR (0.72) MEN1KMT2ARAB9ANPC1SMN1; SMN2
SCHEMBL17084712 0.83 PGR (0.72) MEN1KMT2ARAB9ANPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11718751-B2 Water-borne polymer composition SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2023-08-08 US disclosed