Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4579208 | 0.79 | NOS3 (0.36) | JUNNFKB1NFKB2RELANOS3 | |
| SCHEMBL30238970 | 0.79 | NOS3 (0.36) | JUNNFKB1NFKB2RELANOS3 | |
| SCHEMBL10523216 | 0.78 | JUN (0.41) | JUNNFKB1NFKB2RELANOS3 | |
| SCHEMBL3723468 | 0.75 | MEN1 (0.39) | MEN1KMT2AMAPTTYRO3DYRK1B | |
| SCHEMBL10520740 | 0.74 | NOS3 (0.39) | JUNNFKB1NFKB2RELANOS3 | |
| SCHEMBL31255109 | 0.74 | MEN1 (0.38) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6181403 | 0.74 | RPS6KA5 (0.34) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL31254993 | 0.72 | KDM4E (0.32) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL2126014 | 0.72 | SMN1; SMN2 (0.42) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL8054292 | 0.72 | CSNK1A1 (0.37) | MEN1KMT2AMAPTHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3966206-B1 | HETEROARYLAMINOPYRIMIDINE AMIDE AUTOPHAGY INHIBITORS AND METHODS OF USE THEREOF | DECIPHERA PHARMACEUTICALS LLC (US) | 2023-08-09 | — | — | EP | disclosed |