Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDCBP | O00560 | 8/20 | 0.55 |
| ▸ | SDC2 | P34741 | 8/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25918495 | 0.87 | MAP3K5 (0.47) | SDCBPSDC2ALOX15MAPTSMN1; SMN2 | |
| SCHEMBL20014221 | 0.85 | ALOX15 (0.72) | SDCBPSDC2ALOX15MAPTSMN1; SMN2 | |
| SCHEMBL16266975 | 0.85 | ALOX15 (0.72) | SDCBPSDC2ALOX15MAPTSMN1; SMN2 | |
| SCHEMBL16266972 | 0.85 | ALOX15 (0.72) | SDCBPSDC2ALOX15MAPTSMN1; SMN2 | |
| SCHEMBL25918414 | 0.85 | ALOX15 (0.50) | SDCBPSDC2ALOX15MAPTSMN1; SMN2 | |
| SCHEMBL25919868 | 0.84 | SDCBP (0.44) | SDCBPSDC2ALOX15MAPTSMN1; SMN2 | |
| SCHEMBL25921249 | 0.83 | SDCBP (0.44) | SDCBPSDC2ALOX15MAPTSMN1; SMN2 | |
| SCHEMBL25921269 | 0.83 | SDCBP (0.44) | SDCBPSDC2ALOX15MAPTSMN1; SMN2 | |
| SCHEMBL25918715 | 0.83 | SDCBP (0.44) | SDCBPSDC2ALOX15MAPTSMN1; SMN2 | |
| SCHEMBL25921188 | 0.83 | SDCBP (0.44) | SDCBPSDC2ALOX15MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023132606-A1 | NOVEL ISOINDOLINONE DERIVATIVE COMPOUNDS AS CASPASE INHIBITORS | 주식회사 이노보테라퓨틱스 | 2023-07-13 | — | — | WO | disclosed |