Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL715664 | 1.00 | MAOA (0.31) | MAOAMAOBGAASMN1; SMN2 | |
| Nitric Acid SCHEMBL3260163 | 0.98 | MAOA (0.31) | MAOAMAOBGAASMN1; SMN2 | |
| Acetic Acid SCHEMBL8700134 | 0.90 | GAA (0.36) | GAASMN1; SMN2 | |
| Water SCHEMBL8983722 | 0.86 | MAOA (0.39) | MAOAMAOBGAASMN1; SMN2 | |
| Water SCHEMBL8983758 | 0.86 | MAOA (0.39) | MAOAMAOBGAASMN1; SMN2 | |
| Water SCHEMBL693215 | 0.86 | MAOA (0.39) | MAOAMAOBGAASMN1; SMN2 | |
| Water SCHEMBL1552056 | 0.86 | MAOA (0.39) | MAOAMAOBGAASMN1; SMN2 | |
| Water SCHEMBL8849446 | 0.86 | MAOA (0.39) | MAOAMAOBGAASMN1; SMN2 | |
| Hydrogen Peroxide SCHEMBL15163599 | 0.84 | MAOA (0.38) | MAOAMAOBGAASMN1; SMN2 | |
| SCHEMBL7197365 | 0.84 | MAOA (0.41) | MAOAMAOBGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135785-A1 | PROPYLENE PRODUCTION METHOD | TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) | 2011-11-03 | — | — | WO | disclosed |
| EP-1262232-B1 | Catalysts and process for producing aromatic amines | MITSUBISHI GAS CHEMICAL CO (JP) | 2009-08-12 | — | — | EP | disclosed |
| US-7468342-B2 | Catalysts and process for producing aromatic amines | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2008-12-23 | — | — | US | disclosed |
| EP-1262232-A1 | Catalysts and process for producing aromatic amines | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2002-12-04 | — | — | EP | disclosed |
| US-20020177735-A1 | Catalysts and process for producing aromatic amines | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2002-11-28 | — | — | US | disclosed |