Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL715664 | 0.90 | MAOA (0.31) | GAASMN1; SMN2 | |
| Nitric Acid SCHEMBL2591858 | 0.90 | MAOA (0.31) | GAASMN1; SMN2 | |
| Acetic Acid SCHEMBL2194348 | 0.89 | GAA (0.39) | GAASMN1; SMN2HSD17B3NOTUM | |
| Acetic Acid SCHEMBL11766149 | 0.88 | GAA (0.38) | GAASMN1; SMN2HSD17B3NOTUM | |
| Bicarbonate SCHEMBL4853464 | 0.83 | MAOA (0.34) | GAASMN1; SMN2HSD17B3NOTUM | |
| Bicarbonate SCHEMBL2467504 | 0.83 | MAOA (0.34) | GAASMN1; SMN2HSD17B3NOTUM | |
| Acetamide SCHEMBL7696552 | 0.82 | SMN1; SMN2 (0.38) | GAASMN1; SMN2HSD17B3NOTUM | |
| Pyridine SCHEMBL5593972 | 0.81 | GAA (0.33) | GAASMN1; SMN2HSD17B3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7317965 | 0.79 | MAOA (0.39) | GAASMN1; SMN2 | |
| Propionic Acid SCHEMBL5157894 | 0.79 | HTT (0.35) | GAASMN1; SMN2HSD17B3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998045527-A1 | TEXTILE WITH COLORWASHED ASPECT | CAMPBELL, SARAH, ANN (GB) | 1998-10-15 | — | — | WO | disclosed |