Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 14/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 4/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25323450 | 0.87 | MGLL (0.35) | KCNH2MGLL | |
| SCHEMBL25327453 | 0.82 | CCR1 (0.34) | MGLL | |
| SCHEMBL25327491 | 0.81 | MGLL (0.40) | MGLLSCN9A | |
| SCHEMBL25324592 | 0.80 | MGLL (0.32) | MGLL | |
| SCHEMBL25326166 | 0.79 | MGLL (0.41) | MGLL | |
| SCHEMBL25325243 | 0.79 | MGLL (0.37) | MGLLSCN9A | |
| SCHEMBL25326001 | 0.78 | GAA (0.35) | MGLL | |
| SCHEMBL30553308 | 0.78 | ENPP2 (0.39) | MGLL | |
| SCHEMBL25326619 | 0.78 | MGLL (0.39) | MGLL | |
| SCHEMBL25325303 | 0.77 | MGLL (0.37) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | disclosed |