Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29275514 | 0.83 | GRIK1 (0.36) | CTSDALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL3357407 | 0.80 | CTSD (0.38) | CTSDALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL2946076 | 0.80 | ALDH1A1 (0.39) | ALDH1A1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL12156789 | 0.77 | ALDH1A1 (0.33) | CTSDALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL27781720 | 0.77 | ALDH1A1 (0.33) | CTSDALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL9410921 | 0.76 | ALDH1A1 (0.39) | CTSDALDH1A1HDAC3HDAC1HDAC2 | |
| Ammonia Solution, Strong SCHEMBL28753786 | 0.74 | ALDH1A1 (0.37) | CTSDALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL27677179 | 0.74 | ALDH1A1 (0.37) | CTSDALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL2811489 | 0.72 | ALDH1A1 (0.36) | CTSDALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL13715425 | 0.72 | ALDH1A1 (0.36) | CTSDALDH1A1HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242558-A1 | NICOTINATE AND NICOTINAMIDE RIBOSIDE-BASED COMPOUNDS AND DERIVATIVES THEREOF | New Frontier Bio, Inc. | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242558-A1 | NICOTINATE AND NICOTINAMIDE RIBOSIDE-BASED COMPOUNDS AND DERIVATIVES THEREOF | NAMPT, NNT, NAPRT | CTSD 3357/4885ALDH1A1 1114/4885HDAC3 143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.