SCHEMBL25919792

SCHEMBL25919792

O=C(Oc1ccccc1)c1ccc(C(F)(F)F)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 3/20 0.61
ACR P10323 3/20 0.61
MAPT P10636 3/20 0.60
TDP1 Q9NUW8 1/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
PARP10 Q53GL7 1/20 0.54
KMT2A Q03164 3/20 0.53
MEN1 O00255 2/20 0.53
TMPRSS15 P98073 1/20 0.53
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
MAPK14 Q16539 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.50
NSD2 O96028 1/20 0.50
SRD5A2 P31213 1/20 0.50
CYP1A1 P04798 1/20 0.49
MAOB P27338 1/20 0.49
CYP1B1 Q16678 1/20 0.49
KIF11 P52732 1/20 0.49
NPC1 O15118 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24157322 0.93 MAPT (0.70) PRSS1ACRMAPTTDP1L3MBTL1
SCHEMBL28639038 0.91 PRSS1 (0.71) PRSS1ACRMAPTTDP1L3MBTL1
SCHEMBL9682438 0.91 PRSS1 (0.71) PRSS1ACRMAPTTDP1L3MBTL1
SCHEMBL9065358 0.88 MAPT (0.64) PRSS1ACRMAPTTDP1L3MBTL1
SCHEMBL28641893 0.88 PRSS1 (0.64) PRSS1ACRMAPTTDP1L3MBTL1
SCHEMBL25695962 0.86 PRSS1 (0.56) PRSS1ACRMAPTTDP1L3MBTL1
SCHEMBL678424 0.86 MAPT (0.70) PRSS1ACRMAPTTDP1L3MBTL1
SCHEMBL11682889 0.85 MAPT (0.69) PRSS1ACRMAPTTDP1L3MBTL1
SCHEMBL70034 0.84 PARP10 (0.70) PRSS1ACRMAPTTDP1L3MBTL1
SCHEMBL14640734 0.84 PRSS1 (0.64) PRSS1ACRMAPTTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230242705-A1 ESTER COMPOUND AND RESIN COMPOSITION AJINOMOTO CO., INC. (JP) 2023-08-03 US disclosed
CN-112110817-B Method for preparing diaryl ester compound by high-efficiency catalysis of palladium pyridine 陕西师范大学 2022-07-26 CN disclosed
CN-112110817-A Method for preparing diaryl ester compound by high-efficiency catalysis of palladium pyridine 陕西师范大学 2020-12-22 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242705-A1 ESTER COMPOUND AND RESIN COMPOSITION AFF4, AFF1, AFF2 PRSS1 4522/4885ACR 1200/4885MAPT 2274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.