Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.57 |
| ▸ | ACR | P10323 | 1/20 | 0.57 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24157322 | 0.95 | MAPT (0.70) | MAPTTDP1L3MBTL1PRSS1ACR | |
| SCHEMBL25919792 | 0.88 | PRSS1 (0.61) | MAPTTDP1L3MBTL1PRSS1ACR | |
| SCHEMBL28639038 | 0.86 | PRSS1 (0.71) | MAPTTDP1L3MBTL1PRSS1ACR | |
| SCHEMBL9682438 | 0.86 | PRSS1 (0.71) | MAPTTDP1L3MBTL1PRSS1ACR | |
| SCHEMBL9809037 | 0.86 | PARP10 (0.69) | MAPTTDP1L3MBTL1PARP10KMT2A | |
| SCHEMBL9809043 | 0.86 | PARP10 (0.69) | MAPTTDP1L3MBTL1PARP10KMT2A | |
| Benzaldehyde SCHEMBL7535142 | 0.85 | MAPT (0.57) | MAPTTDP1L3MBTL1PRSS1ACR | |
| SCHEMBL11149811 | 0.84 | PARP10 (0.67) | MAPTTDP1L3MBTL1PRSS1ACR | |
| SCHEMBL28641893 | 0.83 | PRSS1 (0.64) | MAPTTDP1L3MBTL1PRSS1ACR | |
| SCHEMBL6937463 | 0.82 | MAPT (0.66) | MAPTTDP1L3MBTL1PRSS1ACR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546930-B1 | Process for obtaining aryle esters by o-dealkylation and applications | POUDRES & EXPLOSIFS STE NALE (FR) | 1996-02-14 | — | — | EP | disclosed |
| US-5283358-A | Using an aromatic ether and acyl halide; in presence of hexaalkylguanidinium or tetraalkylphosphonium salt catalyst | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1994-02-01 | — | — | US | disclosed |
| EP-0546930-A1 | Process for obtaining aryle esters by o-dealkylation and applications | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1993-06-16 | — | — | EP | disclosed |