⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25895238 | 0.88 | AOC2 (0.34) | — | |
| SCHEMBL23342180 | 0.80 | AOC2 (0.33) | — | |
| SCHEMBL23338585 | 0.80 | HRH3 (0.32) | — | |
| SCHEMBL23342182 | 0.76 | CHRM2 (0.33) | — | |
| SCHEMBL25919762 | 0.73 | NOTUM (0.31) | — | |
| SCHEMBL23338606 | 0.69 | NEK2 (0.40) | — | |
| SCHEMBL27743134 | 0.68 | MMP1 (0.33) | — | |
| SCHEMBL12758825 | 0.65 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL12832224 | 0.65 | CHRM2 (0.35) | — | |
| SCHEMBL5418480 | 0.62 | CYP3A4 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233569-A1 | METHODS FOR DELAYING, PREVENTING, AND TREATING ACQUIRED RESISTANCE TO RAS INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2023-07-27 | — | — | US | disclosed |