Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT3 | O60678 | 1/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2750873 | 0.82 | PRMT3 (0.46) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL13745027 | 0.79 | PRMT3 (0.42) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL23015882 | 0.79 | PRMT3 (0.52) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL10355798 | 0.72 | EPHX1 (0.45) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL12559633 | 0.72 | EPHX1 (0.39) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL10608007 | 0.71 | TSHR (0.37) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL13510606 | 0.71 | PRMT3 (0.34) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL7770101 | 0.71 | — | — | |
| SCHEMBL18372444 | 0.70 | EPHX1 (0.43) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL18372455 | 0.70 | EPHX1 (0.43) | PRMT3CARM1PRMT6PRMT1PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219449-A2 | SUBSTITUTED INDOLE DERIVATIVES AND METHODS OF PREPARATION THEREOF | Kura Oncology, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |