SCHEMBL2750873

SCHEMBL2750873

CCCNCCN(C)CCNC

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PRMT3 O60678 1/20 0.46
CARM1 Q86X55 1/20 0.46
PRMT6 Q96LA8 1/20 0.46
PRMT1 Q99873 1/20 0.46
PRMT8 Q9NR22 1/20 0.46
SIGMAR1 Q99720 2/20 0.40
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
EPHX1 P07099 1/20 0.33
S1PR2 O95136 1/20 0.31
S1PR1 P21453 1/20 0.31
S1PR3 Q99500 1/20 0.31
S1PR5 Q9H228 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
PAOX Q6QHF9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15189352 0.85 PRMT1 (0.50) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL15444588 0.85 CYP2C9 (0.37) SIGMAR1CYP2C9CYP2C19ALDH1A1TSHR
SCHEMBL13745027 0.83 PRMT3 (0.42) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL8347657 0.83 PRMT1 (0.48) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL8503680 0.83 PRMT1 (0.70) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL25556027 0.83 CYP2C9 (0.36) SIGMAR1CYP2C9CYP2C19ALDH1A1TSHR
SCHEMBL4275940 0.82
SCHEMBL21516568 0.82 PRMT3 (0.42) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL25920449 0.82 PRMT3 (0.42) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL1697723 0.82 PRMT1 (0.65) PRMT3CARM1PRMT6PRMT1PRMT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018087635-A1 IMMUNOGENIC POLYSACCHARIDE PROTEIN CONJUGATED COMPRISING A POLYSACCHARIDE DERIVED FROM B STREPTOCOCCUS GBS PFIZER INC. (US) 2018-05-17 WO disclosed
US-8574384-B1 Tags for the sorting of plastics EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2013-11-05 US disclosed
US-20120003271-A1 POLYMER BLENDS The University Court of th University of Edinburgh (GB) 2012-01-05 US disclosed
US-20110226621-A1 TARGET RECOGNITION MOLECULE AND A METHOD FOR IMMOBILIZING THE SAME SHARP KABUSHIKI KAISHA (JP) 2011-09-22 US disclosed
US-20110017599-A1 TARGET RECOGNITION MOLECULE AND A METHOD FOR IMMOBILIZING THE SAME SHARP KABUSHIKI KAISHA (JP) 2011-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120003271-A1 POLYMER BLENDS LDHB, LRBA, LDHA PRMT3 649/4885CARM1 51/4885PRMT6 705/4885
US-20110017599-A1 TARGET RECOGNITION MOLECULE AND A METHOD FOR IMMOBILIZING THE SAME STUB1, EPCAM, CD2BP2 PRMT3 669/4885CARM1 1948/4885PRMT6 378/4885
US-20110226621-A1 TARGET RECOGNITION MOLECULE AND A METHOD FOR IMMOBILIZING THE SAME CD74, EPCAM, CD14 PRMT3 553/4885CARM1 1556/4885PRMT6 354/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.