Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.31 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26686835 | 0.90 | WNT1 (0.33) | LRRK2 | |
| SCHEMBL20939740 | 0.78 | CYP11B1 (0.38) | SSTR4CYP11B1CYP11B2CXCR4 | |
| SCHEMBL18879068 | 0.78 | LRRK2 (0.52) | LRRK2SSTR4CYP11B1CYP11B2 | |
| SCHEMBL30793786 | 0.75 | CREBBP (0.39) | SSTR4CXCR4 | |
| SCHEMBL31207890 | 0.75 | CXCR4 (0.38) | CYP11B1CYP11B2CXCR4 | |
| SCHEMBL19629799 | 0.71 | WNT1 (0.39) | SSTR4 | |
| SCHEMBL30793511 | 0.69 | SPR (0.34) | SSTR4CXCR4 | |
| SCHEMBL31739404 | 0.69 | RPS6KB1 (0.40) | SSTR4CXCR4 | |
| SCHEMBL25910758 | 0.69 | LRRK2 (0.35) | LRRK2 | |
| SCHEMBL25587246 | 0.68 | LRRK2 (0.54) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141300-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2023-07-27 | — | — | WO | disclosed |