Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 17/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 16/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25905716 | 0.86 | DDB1 (0.48) | CRBNDDB1ALDH1A1SMN1; SMN2 | |
| SCHEMBL25575744 | 0.85 | CRBN (0.48) | CRBNDDB1ALDH1A1 | |
| SCHEMBL25905759 | 0.83 | ALDH1A1 (0.47) | CRBNDDB1ALDH1A1SMN1; SMN2 | |
| SCHEMBL25905734 | 0.82 | CRBN (0.42) | CRBNDDB1 | |
| SCHEMBL25905730 | 0.81 | CRBN (0.48) | CRBNDDB1KIF11 | |
| SCHEMBL25216832 | 0.80 | DDB1 (0.40) | CRBNDDB1ALDH1A1 | |
| SCHEMBL30430816 | 0.80 | DDB1 (0.40) | CRBNDDB1ALDH1A1 | |
| SCHEMBL29321374 | 0.79 | CRBN (0.60) | CRBNDDB1KIF11 | |
| SCHEMBL25905651 | 0.79 | CRBN (0.56) | CRBNDDB1 | |
| SCHEMBL25960834 | 0.78 | CRBN (0.48) | CRBNDDB1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234936-A1 | COMPOUND FOR TARGETING AND DEGRADING PROTEIN, AND PREPARATION METHOD THEREFOR AND USE THEREOF | LEADINGTAC PHARMACEUTICAL (SHAOXING) CO., LTD. (CN) | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234936-A1 | COMPOUND FOR TARGETING AND DEGRADING PROTEIN, AND PREPARATION METHOD THEREFOR AND USE THEREOF | IRAK4, IRAK2, IRAK1 | CRBN 221/4885DDB1 1973/4885ALDH1A1 3835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.