Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23937823 | 0.92 | KDM4E (0.43) | KDM4EGAAMAPTIDO1HTR3E | |
| SCHEMBL29952569 | 0.80 | KDM4E (0.56) | KDM4EGAAMAPTIDO1HSD17B10 | |
| SCHEMBL11521138 | 0.75 | KDM4E (0.69) | KDM4EGAAMAPTIDO1HSD17B10 | |
| SCHEMBL29449726 | 0.73 | KDM4E (0.73) | KDM4EGAAMAPTIDO1HSD17B10 | |
| SCHEMBL4495740 | 0.73 | KDM4E (0.73) | KDM4EGAAMAPTIDO1HSD17B10 | |
| SCHEMBL11523761 | 0.73 | KDM4E (0.73) | KDM4EGAAMAPTIDO1HSD17B10 | |
| SCHEMBL20336230 | 0.73 | KDM4E (0.73) | KDM4EGAAMAPTIDO1HSD17B10 | |
| SCHEMBL14185338 | 0.73 | MAPT (0.37) | KDM4EGAAMAPTIDO1HSD17B10 | |
| SCHEMBL24268721 | 0.71 | MAPT (0.39) | KDM4EGAAMAPTIDO1HSD17B10 | |
| SCHEMBL20333672 | 0.71 | KDM4E (0.89) | KDM4EGAAMAPTIDO1HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141432-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |