Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27848349 | 0.81 | KDM4E (0.51) | KDM4EMAPTGAAIDO1KMT2A | |
| SCHEMBL29449726 | 0.80 | KDM4E (0.73) | KDM4EMAPTGAAIDO1KMT2A | |
| SCHEMBL20336230 | 0.80 | KDM4E (0.73) | KDM4EMAPTGAAIDO1KMT2A | |
| SCHEMBL11523761 | 0.80 | KDM4E (0.73) | KDM4EMAPTGAAIDO1KMT2A | |
| SCHEMBL4495740 | 0.80 | KDM4E (0.73) | KDM4EMAPTGAAIDO1KMT2A | |
| SCHEMBL25920707 | 0.80 | KDM4E (0.49) | KDM4EMAPTGAAIDO1KMT2A | |
| SCHEMBL11521138 | 0.78 | KDM4E (0.69) | KDM4EMAPTGAAIDO1KMT2A | |
| SCHEMBL7435270 | 0.75 | KDM4E (0.65) | KDM4EMAPTGAAKMT2AALDH1A1 | |
| SCHEMBL23937823 | 0.72 | KDM4E (0.43) | KDM4EMAPTGAAIDO1LMNA | |
| SCHEMBL17874938 | 0.72 | KDM4E (1.00) | KDM4EMAPTGAAIDO1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |