Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR27 | Q9NS67 | 9/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.52 |
| ▸ | FGB | P02675 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.52 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.52 |
| ▸ | PLEC | Q15149 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.51 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25921058 | 0.91 | GPR27 (0.61) | GPR27KMT2AMEN1ALDH1A1USP2 | |
| SCHEMBL24124854 | 0.83 | POLB (0.65) | GPR27KMT2AMEN1ALDH1A1USP2 | |
| SCHEMBL25920740 | 0.80 | GPR27 (0.68) | GPR27KMT2AMEN1ALDH1A1USP2 | |
| SCHEMBL25920226 | 0.78 | GPR27 (0.68) | GPR27KMT2AMEN1ALDH1A1USP2 | |
| SCHEMBL12010895 | 0.78 | KMT2A (0.83) | GPR27KMT2AMEN1ALDH1A1USP2 | |
| SCHEMBL27180087 | 0.77 | MEN1 (0.58) | GPR27KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30926420 | 0.77 | MEN1 (0.58) | GPR27KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1247477 | 0.77 | JAK2 (0.58) | KMT2AMEN1ALDH1A1USP2SMN1; SMN2 | |
| SCHEMBL30926622 | 0.77 | EGFR (0.53) | GPR27KMT2AMEN1PKMSMN1; SMN2 | |
| SCHEMBL27180430 | 0.77 | EGFR (0.53) | GPR27KMT2AMEN1PKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242496-A1 | SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2023-08-03 | — | — | US | disclosed |
| US-20230242496-A1 | SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242496-A1 | SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA | BCL6, SOX18, BCL3 | GPR27 1850/4885KMT2A 578/4885MEN1 2558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.