Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25922001 | 1.00 | HRH3 (0.37) | HRH3FDPSDNM1SLC6A3SLC6A2 | |
| SCHEMBL14160126 | 0.95 | HRH3 (0.40) | HRH3FDPSDNM1SLC6A3SLC6A2 | |
| SCHEMBL14204509 | 0.93 | HRH3 (0.42) | HRH3SLC6A3SLC6A2SLC6A4SIGMAR1 | |
| SCHEMBL24869964 | 0.93 | HRH3 (0.42) | HRH3SLC6A3SLC6A2SLC6A4SIGMAR1 | |
| SCHEMBL21164045 | 0.93 | HRH3 (0.42) | HRH3SLC6A3SLC6A2SLC6A4SIGMAR1 | |
| SCHEMBL22701318 | 0.91 | SLC6A3 (0.35) | HRH3SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL27953379 | 0.89 | HRH3 (0.36) | HRH3FDPSSLC6A3SLC6A2SLC6A4 | |
| SCHEMBL13609978 | 0.88 | HRH3 (0.45) | HRH3FDPSDNM1SLC6A3SLC6A2 | |
| SCHEMBL2537074 | 0.88 | OPRM1 (0.37) | HRH3FDPSDNM1MAPT | |
| SCHEMBL3261995 | 0.87 | HRH3 (0.38) | HRH3FDPSSLC6A3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023142754-A1 | EZH1/2 INHIBITOR, PREPARATION THEREOF, AND USE THEREOF IN ANTI-TUMOR THERAPY | 江苏天士力帝益药业有限公司 | 2023-08-03 | — | — | WO | disclosed |